普洛药业
Aesthetic & Care Ingredients
API & Intermediate CDMO Finished Dosage Form Aesthetic & Care Ingredients
普洛药业
About ACI
Apeloa ACI specializes in the research, development, production and sales of cosmetics and medical aesthetic raw materials. Our business encompasses contract manufacturing as well as self-operated raw material sales. Leveraging our company's research and development system, along with technology platforms such as biosynthesis and peptide technology, we swiftly respond to clients‘ needs and align with market trends, providing high-quality cosmetic raw material products and product solutions. We offer customized services to leading global cosmetic raw material companies in areas such as UV filters, cosmetic peptides, moisturizing, whitening, and more, while continuously enriching our proprietary product pipeline. The company boasts substantial medical-grade fermentation capacity. Under strict production and quality management systems, we provide users with more reliable medical aesthetic raw materials.
普洛药业
Production Capacity
One bio-production base with certifications for cGMP, ISO9001, ISO14001, OHSAS18001, and IPMS management systems.
One multi-functional biological products production workshop with complete fermentation, extraction, and preparation equipment.
Over 500 m3 of laboratory space with the ability to deliver samples in grams to kilograms.
Total biological fermentation production capacity: 3400 m3 (stainless steel).
With the support of related company resources, Apeloa has complete production capacity for biological-chemical combined projects.
R & D
Medical beauty research fully utilizes synthetic biology + chemical synthesis capabilities to develop medical beauty and cosmetic raw materials. The research platform has rich experience in industrialization of biological fermentation and biocatalysis and focuses on the latest frontier technologies in synthetic biology. It has advanced laboratory equipment and a professional R&D team, with R&D capabilities in strain metabolic pathway design and optimization, protein and peptide design and expression, fermentation process development and optimization, separation and purification process development, biocatalysis and enzyme engineering, etc. It helps to achieve green manufacturing of self-operated medical beauty and cosmetic raw materials and can provide relevant services from R&D to production for customers.
普洛药业
普洛药业
普洛药业
普洛药业
普洛药业
R & D Capabilities
Design and Optimization of Pathways:
Specific biochemical synthesis routes are chosen based on the target product, and the metabolic pathways of the cells are designed and improved. Through biological technologies such as gene editing, engineered or modified microorganisms are constructed or transformed to achieve the production of specific products.

Biological Fermentation & Biocatalysis:
Developing fermentation processes for a variety of industrial microorganisms such as E. coli, actinomycetes, yeast, and molds, we optimize the fermentation process through experimental research and computational modeling, and scale it up from the laboratory to the industrial production scale. We also engage in the construction and modification of enzymes, immobilization of enzymes, and optimization of enzyme-catalyzed processes. By combining enzyme catalysis with chemical synthesis, we efficiently synthesize a range of products.

Separation and Purification Technology:
With expertise in organic synthesis, chemical engineering, peptide separation, chiral separation, fermentation product separation, and equipped with a variety of separation and purification equipment including membrane devices, centrifugal equipment and preparative chromatography, we are engaged in the development of separation and purification technology for various biological fermentation and biotransformation products, as well as the scale-up of processes.

Engineering Design and Scale-Up Technology:
With the ability to control processes, design equipment, and apply scaling strategies, this program uses simulation and computational tools to predict and optimize performance, successfully scaling laboratory-scale processes to industrial production levels while ensuring production efficiency and product quality while meeting scaled-up demands.
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